PUBLICATIONS2018-03-30T11:19:49+00:00

Publications

Rowley PA, Patterson K, Sandmeyer SB, Sawyer SL. (2018) Control of Yeast Retrotransposons Mediated Through Nucleoporin Evolution. PLoS Genetics, in press

Stabell AC, Meyerson NR, Gullberg RC, Gilchrist AR, Webb KJ, Old WM, Perera R, Sawyer SL. (2018) Dengue viruses cleave STING in humans but not in non-human primates, their presumed natural reservoir. eLIFE, e31919.

Meyerson NR, Stabell AC, Vieira D, Diaz-Griffero F, Sawyer SL. (2018) Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes. PLoS Pathogens, 14(3):e1006906.

Meyerson NR, Zhou L, Guo YR, Zhou C, Tao YJ, Krug RM, Sawyer SL. (2017) TRIM25 is a restriction factor that specifically targets influenza virus ribonucleoproteins to block the onset of RNA chain elongation. Cell Host and Microbe, 22(5):627-638.e7

Nahabedian J, Sharma A, Kaczmarek ME, Wilkerson GK, Sawyer SL, Overbaugh J. (2017) Owl monkey CCR5 reveals synergism between CD4 and CCR5 in HIV-1 entry. Virology, 512:180-186.

Stabell AC, Hawkins J, Li M, Gao X, David M, Press WH, Sawyer SL (2016) Non-human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins. PLoS Pathogens 12(12): e1006066.

Lou DI, Kim ET, Meyerson NR, Pancholi NJ, Mohni KN, Enard D, Petrov DA, Weller SK, Weitzman MD, Sawyer SL (2016). An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates. Cell Host & Microbe, 20(2), 178–188.

Wilke CO and Sawyer SL (2016). At the mercy of viruses. eLIFE, 5, e16758.

Rowley PA, Ho B, Bushong S, Johnson A, Sawyer SL (2016) XRN1 Is a Species-Specific Virus Restriction Factor in Yeasts. PLoS Pathogens 12(10): e1005890.

Ng M, Ndungo E, Kaczmarek ME, Herbert AS, Binger T, Kuehne AI, Jangra RK, Hawkins JA, Gifford RJ, Biswas R, Demogines A, James RM, Yu M, Brummelkamp TR, Drosten C, Wang L-F, Kuhn JH, Muller MA, Dye JM, Sawyer SL, Chandran K. (2015). Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats. eLIFE, 4, e11785.

Hussmann JA, Patchett S, Johnson A, Sawyer S, Press WH (2015). Understanding Biases in Ribosome Profiling Experiments Reveals Signatures of Translation Dynamics in Yeast. PLoS Genetics, 11(12), e1005732.

Kerr SA, Jackson EL, Lungu OI, Meyer AG, Demogines A, Ellington AD, Georgiou G, Wilke CO,  Sawyer SL (2015). Computational and Functional Analysis of the Virus-Receptor Interface Reveals Host Range Trade-Offs in New World Arenaviruses. Journal of Virology, 89(22), 11643–11653.

McBee RM, Rozmiarek SA, Meyerson NR, Rowley PA, Sawyer SL (2015). The effect of species representation on the detection of positive selection in primate gene data sets. Molecular Biology and Evolution, 32(4), 1091–1096.

Meyerson NR, Sharma A, Wilkerson GK, Overbaugh J, Sawyer SL (2015). Identification of Owl Monkey CD4 Receptors Broadly Compatible with Early-Stage HIV-1 Isolates. Journal of Virology, 89(16), 8611–8622.

Hussmann JA, Lou DI, Sawyer SL, Press WH (2014). Reply to Schmitt et al.: Data-filtering schemes for avoiding double-counting in circle sequencing. Proc Natl Acad Sci USA, 111(16), E1561.

Peng L, Adler M, Demogines A, Borrell A, Liu H, Tao L, Tepp WH, Zhang SC, Johnson EA, Sawyer SL, Dong M (2014). Widespread Sequence Variations in VAMP1 across Vertebrates Suggest a Potential Selective Pressure from Botulinum Neurotoxins. PLoS Pathogens, 10(7), e1004177.

Lou DI, McBee RM, Le UQ, Stone AC, Wilkerson GK, Demogines AM, Sawyer SL (2014). Rapid evolution of BRCA1 and BRCA2 in humans and other primates. BMC Evolutionary Biology, 14, 155.

Meyerson NR, Rowley PA, Swan CH, Le DT, Wilkerson GK, Sawyer SL (2014). Positive selection of primate genes that promote HIV-1 replication. Virology, 454-455, 291–298.

White TE, Brandariz-Nuñez A, Valle-Casuso JC, Knowlton C, Kim B, Sawyer SL, Diaz-Griffero F (2014). Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility. Virology, 460-461(C), 34–44.

Demogines A, Abraham J, Choe H, Farzan M, Sawyer SL (2013). Dual host-virus arms races shape an essential housekeeping protein. PLoS Biology, 11(5), e1001571.

Lou DI, Hussmann JA, McBee RM, Acevedo A, Andino R, Press WH,  Sawyer SL (2013). High-throughput DNA sequencing errors are reduced by orders of magnitude using circle sequencing. Proc Natl Acad Sci USA, 110(49), 19872–19877.

Abrams AJ, Cannatella DC, Hillis DM, Sawyer SL (2013). Recent host-shifts in ranaviruses: signatures of positive selection in the viral genome. J General Virology, 94(Pt 9), 2082–2093.

Malfavon-Borja R, Sawyer SL, Wu LI, Emerman M, Malik HS (2013). An evolutionary screen highlights canonical and noncanonical candidate antiviral genes within the primate TRIM gene family. Genome Biology and Evolution, 5(11), 2141–2154.

Voit RA, McMahon MA, Sawyer SL, Porteus MH (2013). Generation of an HIV Resistant T-Cell Line by Targeted “Stacking” of Restriction Factors. Molecular Therapy, 21(4), 786–795.

Kaelber JT, Demogines A, Harbison CE, Allison AB, Goodman LB, Ortega AN, Sawyer SL, Parrish CR (2012). Evolutionary reconstructions of the transferrin receptor of Caniforms supports canine parvovirus being a re-emerged and not a novel pathogen in dogs. PLoS Pathogens, 8(5), e1002666.

Demogines A, Farzan M, Sawyer SL (2012). Evidence for ACE2-Utilizing Coronaviruses (CoVs) Related to Severe Acute Respiratory Syndrome CoV in Bats. Journal of Virology, 86(11), 6350–6353.

Demogines A, Truong KA, Sawyer SL (2012). Species-specific features of DARC, the primate receptor for Plasmodium vivax and Plasmodium knowlesi. Molecular Biology and Evolution, 29(2), 445–449.

Sawyer SL and Elde NC (2012). A cross-species view on viruses. Current Opinion in Virology, 2(5), 561–568.

Lee K, Mulky A, Yuen W, Martin TD, Meyerson NR, Choi L, Yu H, Sawyer SL, KewalRamani VN (2012). HIV-1 Capsid-Targeting Domain of Cleavage and Polyadenylation Specificity Factor 6. Journal of Virology, 86(7), 3851–3860.

Han K, Lou DI, Sawyer SL (2011). Identification of a genomic reservoir for new TRIM genes in primate genomes. PLoS Genetics, 7(12), e1002388.

Meyerson NR, Sawyer SL (2011). Two-stepping through time: mammals and viruses. Trends in Microbiology, 19(6), 286–294.

Demogines A, East AM, Lee J-H, Grossman SR, Sabeti PC, Paull TT, Sawyer SL (2010). Ancient and recent adaptive evolution of primate non-homologous end joining genes. PLoS Genetics, 6(10), e1001169.

Johnson WE and Sawyer SL (2009). Molecular evolution of the antiretroviral TRIM5 gene. Immunogenetics, 61(3), 163–176.

Tareen SU, Sawyer SL, Malik HS, Emerman M. (2009). An expanded clade of rodent Trim5 genes. Virology, 385(2), 473–483.

Sawyer SL, Emerman M, Malik HS. (2007) Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals. PLoS Pathogens, 3(12): e197.

Sawyer SL and Malik HS. (2006) Positive selection of yeast nonhomologous end-joining genes and a retrotransposon conflict hypothesis. Proc Natl Acad Sci USA, 103(47): 17614-9.

Sawyer SL, Wu LI, Akey JM, Emerman M, Malik HS. (2006) High Frequency Persistence of an Impaired Allele of the Retroviral Defense Gene TRIM5 in Humans. Current Biology, 16(1): 95-100.

Sawyer SL, Wu LI, Emerman M, Malik HS. (2005) Positive selection of primate TRIM5 identifies a critical species-specific retroviral restriction domain. Proc Natl Acad Sci USA, 102(8): 2832-7.

Sawyer SL, Emerman M, Malik HS. (2004) Ancient adaptive evolution of the primate antiviral DNA editing enzyme, APOBEC3G. PLoS Biology, 2(9): e275.

Sawyer SL, Cheng IH, Chai W, Tye BK. (2004) Mcm10 and Cdc45 Cooperate in Origin Activation in Saccharomyces cerevisiae. Journal of Molecular Biology, 340: 195-202.

Tye BK and Sawyer S. (2000) The hexameric eukaryotic MCM helicase: building symmetry from nonidenticle parts. Journal of Biological Chemistry, 275(45): 34833-6.

Homesley L, Lei M, Kawasaki Y, Sawyer S, Christensen T, Tye BK. (2000) Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins. Genes and Development, 14(8): 913-926.